Research On Animal Production

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     To investigate the effects of feed restriction and Coenzyme Q₁₀ supplementation on incidence of ascites and immune system in broilers, a factorial arrangement with completely randomized design with two levels of CoQ₁₀ (0, 20 mg/kg of diet) and three levels of feed restriction (0, 10 and 20 %) was carried out. Six hundreds 1-d-old Arian broiler chicks were randomly allocated into 6 groups with 5 replicates and 20 chicks in each replicate. From d 15, the diets were supplemented with CoQ₁₀ at levels of 0 and 20mg/kg. During the experimental period (42 days) chick mortality for ascites problem were investigated. Also, the RV/TV ratio, total red blood cell (RBC), hematocrit (PCV), hemoglobin(Hb), leukocyte differential counts (including heterophils (H), lymphocytes (L), H: L ratio) were investigated. In this experiment SRBC response, IgG and IgM were investigated as immune responses. According to results, RV/TV ratio, hematocrits, hemoglobin and  total red blood cell number were not affected by feed restriction and CoQ₁₀ (p>0.05). Feed restriction had no positive effect on SRBC response but it was affected by CoQ10 which found to be significant (p<0.07). Feed restriction and CoQ₁₀ had not significant effect on immunoglobulin M and G (p>0.05). White blood cells, lymphocytes, hetrophils and also hetrophil to lymphocytes ratio were not affected by feed restriction and CoQ₁₀ (p>0.05).
 

Keywords: Feed restriction, Coenzyme Q10, Ascites syndrome, Immune system, Broiler chickens

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