In this research, influence of Revabio enzyme on improving anti-nutritional of wheat bran (high in fiber, non-starch polysaccharides and phytate) were investigated. The total number of 320 commercial male broiler chicks (Ross 308) in a factorial experiment 4×2 with four replications were used. Treatment consists of four levels of wheat bran (0, 10, 15 and 20 percent) and two levels of enzyme (0 and 0.05 percent), respectively. The experiment was carried on 42 days and divided into 3 period of starter, grower and finisher. Feed intake, body weight gain and feed conversion ratio (FCR) were determined for each week of experiment. In day 42, 2 birds from each unit were slaughtered and blood sampling was taken. The results showed that including wheat bran in the diets had no significant effect on weight gain and feed conversion ratio in total period. With increasing wheat bran levels, the average of weight gain was decreased. Adding enzyme to diets significantly improved weight gain and feed conversion ratio. The use of wheat bran in the diet reduced blood glucose and incresed zinc consentration significantly (P<0.05) but did not significant effect on other serum parameters. Revabio increased serum concentrations of triglyceride, cholesteroand significantly (P<0.05). Also Chicks fed with enzyme had higher serum concentrations of calcium, phosphorus consentration. Results of this experiment showed that, addition of enzyme on diets can improve anti nutritional of wheat bran and use wheat bran as part of diets in broiler diets.
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