Volume 8, Issue 15 (6-2017)                   rap 2017, 8(15): 105-114 | Back to browse issues page

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The Effect of Different Levels of Levamisole Drug on Performance and Related Parameters with Immune System in Broiler Chickens. rap. 2017; 8 (15) :105-114
URL: http://rap.sanru.ac.ir/article-1-760-en.html
Abstract:   (1419 Views)

     This experiment was conducted to study the effect of different levels of levamisole on performance and related parameters with immune system in Cobb 500 strain male broilers. The experiment was carried out a completely randomized design, with 300 male broiler chickens in four treatments and five replicates 15 birds/replicates. The experimental groups consisted of zero, 2.5, 5 and 7.5 mg per kg live body weight of levamisole in the third week. Parameters examined include performance and related parameters with immune system, phagocytic activity test, antibody titers against Newcastle, Influenza and Gambro disease and organs weight involved in immune system. Results showed that adding of levamisole into diet had no effect on body weight gain, feed intake and feed conversion ratio in broilers. Adding of levamisole into diet increased the number of lymphocytes, monocytes and heterophils in broiler (P<0.05). Levamisole improved cellular immune system in broiler chickens (P<0.05). Phagocytic activity was increased in broilers treated with levamisole at 7.5 kg per kg of live body weight (P<0.05). Use of levamisole in broiler chickens increased antibody titers than controls, but this increase was not significant at 28 days except against Gambro disease. At 42 days, Levamisole had a significant effect on the size of the bursa Fabricius in broilers (P<0.05). Also, there were no mortalities in any of the experimental treatments. It seems, levamisole may have a beneficial effect on the immune system of broiler chickens. Between three different levels of levamisole, the levels of 5 and 7.5 mg per kg of live body weight had better resultion parameters involved in immune system of broiler chicks.

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Type of Study: Research | Subject: Special
Received: 2017/06/17 | Revised: 2017/06/19 | Accepted: 2017/06/17 | Published: 2017/06/17

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