Volume 8, Issue 15 (6-2017)                   rap 2017, 8(15): 25-32 | Back to browse issues page


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(2017). Efficacy of Aqueous Extract of Thymus Daenensis to Ameliorate the Adverse Effects of Aflatoxin in Japanese Quail. rap. 8(15), 25-32. doi:10.29252/rap.8.15.25
URL: http://rap.sanru.ac.ir/article-1-748-en.html
Abstract:   (5562 Views)

This study evaluated the efficacy of aqueous extract of Thymus daenensis to ameliorate the adverse effects of aflatoxin B1 (AFB1) in Japanese quail. The experiment was conducted as a 2×2 factorial arrangement in a completely randomized design with two levels of aflatoxin (0 and 500µg/kg) and two levels of aqueous extract of T. daenensis (0 and 2000 mg/kg). Each of the 4 dietary treatments was fed to five replicate cages (4 birds/cage) from 24 to 45 days of age. The results showed that Aflatoxin and extract did not have any effect on the histo-morphology of jejunum of birds (P < 0.05). Aflatoxin significantly increased relative weight of liver. Observation of liver microscopy showed that hepatocytes fat content was increased. Extract significantly decreased relative weight of liver. There was an interaction between aflatoxin and extract on relative weight of liver (P < 0.01), so that negative effect of aflatoxin on relative weight of liver was significantly decreased in birds offered diet with extract. Aflatoxin B1 significantly increased alanine aminotransferase and aspartate aminotransferase, but extract significantly decreased alanine aminotransferase and aspartate aminotransferase. There was an interaction between aflatoxin and extract on above enzymes (P < 0.05), so that serum alanine aminotransferase and aspartate aminotransferase were decreased in birds offered diets with aflatoxin and extract. In conclusion, our results showed that addition of aqueous extract of Thymus daenensis reduced the adverse effects produced by the presence of AFB1 in Japanese quail diets.

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Type of Study: Research | Subject: Special
Received: 2017/06/17 | Revised: 2017/08/27 | Accepted: 2017/06/17 | Published: 2017/06/17

References
1. Applegate, T.J., G. Schatzmayr, K. Pricket, C. Troche and Z. Jiang. 2009. Effect of aflatoxin culture on intestinal function and nutrient loss in laying hens. Poultry Science, 88: 1235-1241. [DOI:10.3382/ps.2008-00494]
2. Aravind, K.L., V.S. Patil, G. Davegowda, B. Umakantha and S.P. Ganpule. 2003. Efficacy of esterified glucomannan to counteract mycotoxicosis in naturally contaminated feed on performance and serum biochemical and hematological parameters in broilers. Poultry Science, 82: 571-576. [DOI:10.1093/ps/82.4.571]
3. Bintvihok, A. and S. Kositcharoenkul. 2006. Effect of dietary calcium propionate on performance, hepatic enzyme activities and aflatoxin residues in broilers fed a diet containing low levels of aflatoxin B1. Toxicology, 47: 41-46. [DOI:10.1016/j.toxicon.2005.09.009]
4. Chattopadbyay, S.K., P.K. Taskar, O. Schwabe, Y.T. Dasand H.D. Brown. 1985. Clinical and biochemical effects of aflatoxin in feed ration of chicks. Cancer Biochimtry Biophysics, 8: 67-75.
5. Demir, E., S. Sarica, M.A. Ozcan and M. Suicmez. 2005. The use of natural feed additives as alternative to an antibiotic growth promoter in boiler diets. Archiv Fur Geflugelkunde, 69: 110-116.
6. Eaton, D.L. and J.D. Groopman. 1994. The Toxicology of aflatoxins. academic press, New York, 383-424.
7. Farag, R.S., Z.M.A. Badi, F.M. Hewedi and G.S.A. El-Baroty. 1989. Antioxidant activity of some spice essential oils on linoleic acid oxidation in aqueous media. Journal of the American Oil Chemists' Society, 66: 792-799. [DOI:10.1007/BF02653670]
8. Gorran, A., M. Farzaneh, M. Shivazad, M. Rezaeian and A.R. Ghassempour. 2013. Aflatoxin B1-reduction of aspergillusflavus by three medicinal plants (Lamiaceae). Food Control, 31: 218-223. [DOI:10.1016/j.foodcont.2012.09.024]
9. Gowda, N.K.S., D.R. Ledoux, G.E. Rottinghaus, A.J. Bermudez and Y.C. Chen. 2008. Efficacy of turmeric (Curcuma longa), containing a known level of curcumin and a hydrated sodium calcium aluminosilicate to ameliorate the adverse effects of aflatoxin in broiler chicks. Poultry science, 87: 1125-1130. [DOI:10.3382/ps.2007-00313]
10. Hema, R., S. Kumaravel and A. Sivasubramanian. 2010. Antimicrobial activity of some of the indian spices against food borne pathogens. New York Science Journal, 3: 191-193.
11. Hsieh, D.P.H. 1979. Basic metabolic effects of mycotoxins in interactions of mycotoxins in animal production. Proc. Symp 43-55 pp., Washington, DC.
12. Hussain, Z., M.Z. Khan and Z.U. Hassan. 2008. Production of aflatoxins from aspergillusflavus and acute aflatoxicosis in young broiler chicks. Pakistan Journal of Agricultural Sciences, 45: 95-102.
13. Jamroz, D., T. Wertelecki, M. Houszka and C. Kamel. 2006. Influence of diet type on the inclusion of plant origin active substances on morphological and histochemical characteristics of the stomach and jejunum walls in chicken. Journal of Animal Physiology and Animal Nutrition, 90: 255-268. [DOI:10.1111/j.1439-0396.2005.00603.x]
14. Jassar, B.S. and B. Singh. 1993. Biochemical changes in experimental aflatoxicosis in broiler chickens. Indian Jornal of Animal Science, 63: 847-848.
15. Lòpez, C., L. Ramos, S. Rámadan, L.Bulácio and J. Pérez. 2001. Distribution of aflatoxin m1 in cheese obtained from milk artificially contaminated. International Journal Food Microbiology, 64: 211-215. [DOI:10.1016/S0168-1605(00)00444-X]
16. Luna, L.G. 1968. Manuel of histologic staining methods of the armed forces institute of anthology, third ed. McGraw-Hill, New York.
17. Madheswaran, R., C. Balachandran and B. Murali Manohar. 2004. Influence of dietary culture material containing aflatoxin and t2 toxin on certain serum biochemical constituents in Japanese Quail. Mycopathologia, 158: 337-341. [DOI:10.1007/s11046-005-8399-8]
18. Mani, K., K. Sundaresan and K. Viswanathan. 2000. Performance of commercial broiler strains under experimental aflatoxicosis. Indian Journal Poultry Science, 35: 176-180.
19. McGavin, M.O., W.W. Cartton and J.F. Zachary. 2001. Thomsons special veterinary pathology.3th. ed., Mosby, St. Louis, USA, 110 pp.
20. Merkley, J.W., R.J. Maxwell, J.G. Phillips and W.E. Huff. 1987. Hepatic fatty acid profiles in aflatoxin-exposed broilers chickens. Poultry Science, 66: 59-67. [DOI:10.3382/ps.0660059]
21. Mirabolfathi, M. 2009. Proceedings of the Mycotoxin contamination of cereals and nutsin Iran. 18th Iranian Plant Protection Congress, 32-36 pp., Hamadan, Iran.
22. Namkung, H., M. Li, J. Gong, H. Yu, M. Cottrill and C.F.M. De Lange. 2004. Impact of feeding blends of organic acids and herbal extracts on growth performance, gut microbiota and digestive function in newly weaned pigs. Candain Journal Animal Science, 84: 697-704. [DOI:10.4141/A04-005]
23. Park, D.L. 1993. Controlling Aflatoxin in Food and Feeds. Food Technology, 47: 92-96.
24. Raju, M.V.L.N. and G. Devegowda. 2000. Influence of esterified-glucomannan on performance and organ morphology, serum biochemistry and hematology in broilers exposed to individual and combined mycotoxicosis (Aflatoxin, Ochratoxin and T-2 Toxin). British Poultry Science, 41: 640-650. [DOI:10.1080/713654986]
25. Rasooli, I. and M.R. Abyaneh. 2004. Inhibitory Effects of thyme oils on growth and aflatoxin production by Aspergillusparasiticus. Food Control, 15: 479-483. [DOI:10.1016/j.foodcont.2003.07.002]
26. Razzaghi-Abyaneh, M., M. Shams-Ghahfarokhi, T. Yoshinari, M.B. Rezaee, K. Jaimand, H. Nagasawa and S. Sakuda. 2008. Inhibitory effects of saturejahortensis l. essential oil on growth and aflatoxin production by Aspergillusparasiticus. International Journal of Food Microbiology, 123: 228-233. [DOI:10.1016/j.ijfoodmicro.2008.02.003]
27. Reddy, K.R.N., C.S. Reddy and K. Muralidharan. 2009. Potential of botanicals and biocontrol agents on growth and aflatoxin production by Aspergillusflavus Infecting Rice Grains. Food Control, 20: 173-178. [DOI:10.1016/j.foodcont.2008.03.009]
28. Rizvi, A.V.R., A.R. Shakoori and S.M. Rizvi. 1990. Aflatoxin Contamination of Commercial Poultry Feeds in Punjab. Pakistan Journal of Zoology, 22: 387-398.
29. SAS. 1990. User's Guide. Release 92, Cary, NC, USA, SAS Institute Inc.
30. Shotwell, O.L., C.V. Hesseltine, R.D. Stubblefleld and W.G. Sorenson. 1966. Production of Aflatoxin on Rice. Applied Microbiology, 14: 425-429.
31. Sinha, K.K. and D. Bhatnagar. 1998. Mycotoxin in Agriculture and Food Safety. Marcel Dekker. Inc.New York, 511 pp.
32. Trucksess, M.W., L. Stoloff, K. Young, R.D. Wyatt and B.L. Miller. 1983. Aflatoxicol and aflatoxins B1 and M1 in Eggs and Tissues of Laying Hens Consuming Aflatoxin-Contaminated Feed. Poultry Science, 62: 2176-2182. [DOI:10.3382/ps.0622176]
33. Wan, X.L., Z.B. Yang, W.R. Yang, S.Z. Jiang, G.G. Zhang, S.L. Johnston and F. Chi. 2013. Toxicity of Increasing Aflatoxin B1 Concentrations from Contaminated Corn with or without clay Adsorbent Supplementation in Ducklings. Poultry Science, 92: 1244-1253. [DOI:10.3382/ps.2012-02748]
34. Yang, J.1., F. Bai1, X. Lv. Zhang, S. Bai, L.X. Zhao, X. Peng, Y. Li. Ding and J. Zhang. 2012. Effects of Feeding Corn Naturally Contaminated with AFB1 and AFB2 on Performance and Aflatoxin Residues in Broilers. Czech Journal Animal Science, 57: 506-515. [DOI:10.17221/6383-CJAS]
35. Yunus, A.W., E. Razzazi-Fazeli and J. Bohm. 2011. Aflatoxin B1 in Affecting Broiler's Performance, Immunity and Gastrointestinal Tract: A Review of History and Contemporary Issues. Toxins, 3: 566-590. [DOI:10.3390/toxins3060566]

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