An experiment was done for studying different levels of Ca & P (with and without Phytaze enzyme) on liver enzymes and blood parameters in Arian broiler chickens. Two hundred eighty eight broiler chicken were used in a completely randomized design with 6 treatments and 4 replicates with 12 chickens in each floor pen.  Broiler chickens were fed with different levels of Ca and P (with or without Phytaze enzyme). Treatments included: control group (0.1Ca, 0.5P %) and other treatments were 15% and 30% Ca and P lower than control diet (with and without Phytaze enzyme), 15% Ca & P more than control diet. The results showed that in diet with 15% Ca and P lower than control group had maximum feed intake, body weight gain and minimum feed conversion ratio in total period. The liver of AST, ALP and LDH enzymes concentration were affected by different treatments. But ALT was not affected by treatments. Treatment significantly affected of blood parameter including P, N and K, but not effected on the Ca concentration in 21 and 42 days. In general, it can be concluded that the diet with 15% Ca and P lower than control group resulted highest feed consumption, body weight gain and best feed conversion ratio.